Enoxaparin Sodium BP
Composition :
Active ingredient :
Enoxaparin sodium Solvent :Water for injections.
Each ml of the solution contains :
10000 anti-Xa IU equivalent to
100mg Enoxaparin sodium.
Cardinex-40 : 4000 anti-Xa IU/0.4ml.
Cardinex-60 : 6000 anti-Xa IU/0.6ml.
Cardinex-80 : 8000 anti-Xa IU/0.8ml.
Indication : Cardinex is indicated for o Prophylaxis of venous thromboembolic disease (prevention of blood clot formation in the veins). Prevention of thrombus formation in the extracorporal circluation during haemodialysis.Treatment of unstable angina and non-Q-wave myocardial infarction during acute stage.Treatment of established deep vein thrombosis with or without pulmonary embolism.
Dosage and administration :
1mg (0.01ml) of enoxaparin corresponds approximately to 100 anti-Xa I.U. Enoxaparin should be injected by deep SUBCUTANEOUS ROUTE in prophylactic and curative treatment and by INTRAVASCULAR ROUTE during haemodialysis. Do not administer by INTRAMASCULAR ROUTE. Prophylaxis of venous thrombo-embolic disease in medical patients.
The recommended dose of enoxaparin sodium is 4000 anti-Xa IU (0.4ml) once daily. Treatment of established deep vein thrombosis with or without pulmonary embolism: A dose of 1mg/kg should be given subcutaneously every 12 hours. The duration of the treatment should not exceed a preiod of 10 days. Treatment of unstable angina and non-Q-wave myocardial infarction : A dose of 1mg/kg should be given subcutaneously every 12 hours. The recommended treatment should be prescribed for a period of 2 to 8 days, until clinical stabilization of the patient. Elderly : No dosage adjustment is necessary in preventive therapy. Children : Enoxaparin is not recommended in children. Or, as directed by the registered physician.
Use in pregnancy and lactation : Enoxaparin has been assigned to pregnancy category B by the FDA. There are no controlled data in women pregnancy. It can be used in pregnancy if potential benefits outweigh the risk or as directed by the registered physician. Enoxaparin is likely to be excreted into the breast milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the benefit of the drug to the mother.
Packing :
Cardinex-40 : 1x1's prefilled syringe BP (0.4ml) in a blister pack.
Cardinex-60 : 1x1's prefilled syringe BP (0.6ml) in a blister pack.
Cardinex-80 : 1x1's prefilled syringe BP (0.8ml) in a blister pack.
