Itraconazole
Composition: Each capsule contains Itraconazole pellets eqv. to Itraconazole USP 100mg.
Indications: Itraconazole Capsules are indicated for the treatment of Vulvovaginal candiasis, Oropharyngeal candiasis, Pityriasis versicolor, tinea pedis, tinea cruris, tinea corporis, tinea manuum, Onychomycosis, Histoplasmosis. It is indicated in the treatment of following systematic fungal conditions when first-line systemic anti-fungal therapy is inappropriate or has proved ineffective: Cryptococcosis (including cryptococcal meningitis), Aspergillosis, Candiasis. It is also used in maintenance therapy in AIDS to prevent relapse of underlying fungal infections and in the prevention of fungal infection during prolonged neutropenia.
Dosage & Administration: This
capsule must be taken immediately after a meal for maximal absorption.
· For Non-Systemic fungal infections: Vulvovaginal candidiasis: 200mg twice daily for 1 day. Pityriasis versicolor: 200mg once daily for 7 days. Tinea corporis and tinea cruris: 100mg once daily for 15 days or 200mg once daily for 7 days. Tinea pedis and tinea manuum: 100mg once daily for 30 days. Oropharyngeal candidosis: 100mg once daily (200mg once daily in AIDS or neutropenia) for 15 days. Onychomycosis (toenails with or without fingernails involvement): 200mg once daily for 3months. or course (pulse) of 200mg twice daily for 7 days, subsequent courses repeated after 21days interval; fingernails two courses and toenails three courses.
· For Systemic fungal infections: Aspergillosis: 200mg once daily for 2-5 months, Increase dose to 200mg twice daily in case of invasive or disseminated disease. Candidiasis: 100-200 mg once daily for 3 weeks-7 months, Increase dose to 200 mg twice daily in case of invasive or disseminated disease. Non-meningeal cryptococcosis: 200mg once daily for 10 weeks. Cryptococcal meningitis: 200mg once daily for 2 months- 6 months. Histoplasmosis: 200mg once daily- twice daily for 8months. Maintenance in AIDS: 200mg once daily until immune recovery. Prophylaxis in neutropenia: 200mg twice daily until immune recovery.
The dose and duration of treatment for systemic fungal disease should be adjusted depending on the clinical response. Or, as directed by the registered physician.
Use in pregnancy and lactation: Not recommended during pregnancy and
lactation, unless otherwise indicated by the physician.
Packing: Each box contains 20 capsules in Alu-Alu blister pack.
