COZYME

Coenzyme Q10 USP

Composition: Cozyme-30 : Each Soft Gelatin Capsule contains Coenzyme Q10 (Ubidecarenone) USP 30mg.

Cozyme-60 : Each Soft Gelatin Capsule contains Coenzyme Q10 (Ubidecarenone) USP 60mg.

Indications: Coenzyme Q1O is indicated for 1. Known coenzyme QI 0 deficiency; 2.Heart failure in adults; 3. To reduce the risk of future cardiac events in patients with recent myocardial infarction; 4. High blood pressure; 5. Isolated systolic hypertension; 6. For preventing migraine headache; 7. Parkinson’s diseases: 8. Infertility in men: 9. Muscular dystrophy; 10. Pre-eclampsia.

Dosage & Administration: Daily doses of Coenzyme 010 range from 30mg - 300mg in divided doses. The following dose have been studied in scientific research : ORAL: Known coenzymeQlO deficiency : 150mg/day; Heart failure in adults : 100mg/day in 2-3 divided doses; To reduce the risk of future cardiac events in patients with recent myocardial infarction : 120mg/day in 2 divided doses; High blood pressure: 120- 200mg/day in 2 divided doses; Isolated systolic hypertension: 60mg 2 times/day; For preventing migraine : 100mg 3 times/day, 1-3mg/kg is used in pediatric and adolescent patients; Parkinson’s disease: 300mg, 600mg, 1200mg and 2400mg/day in 3-4 divided doses; Infertility in men: 200-300mg/day; MAscular dystrophy: 100mg/day; Pre-eclamsia:100mg 2 times/day starting at week 20 to pregnancy until delivery. Or, as directed by the registered physician.

Pregnancy & Lactation: Because of lack of information on long term safety, pregnant women and nursing mothers should avoid Coenzyme Q10. Drug Interactions Warfarin: Supplemental Coenzyme 010 may decrease the effectiveness of warfarin. Statins: The stalin drugs are known to decrease Coenzyme Qi 0 levels in humans. Doxorubucin : Coenzyme Q10 may help to increase the cardiotoxicity of doxorubicin. Antidia betic medications: Coenzyme 010 may improve glycemic control in some type II diabetics. If this were to occur, antidiabetics medications might need appropriate adjusting. Beta blockers: Some beta blockers, in particular propanolol, have been reported to inhibit some Coenzyme 010 dependent enzymes.

Packing: Cozyme-30: 3x10’s soft capsules in blister pack.

Cozyme-60: 2x10’s soft capsules in blister


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