ONDASON Tablet

Ondansetron USP

Composition : Ondansetron 8mg Tablet.

Indication : It is used in the management of nausea and vomiting induced by cytotoxic chemotherapy and radiotherapy. It is also used for the prevention and treatment of postoperative nausea and vomiting.

Dosage and administration :

1) Prevention of Nausea and Vomiting Associated Chemotherapy :

Adults : The recommended adult oral dosage for highly emetogenic cancer chemotherapy is 24 mg given as three 8 mg tablets administered 30 minutes before the start of emetogenic chemotherapy. For moderate emetogenic cancer chemotherapy the recommended adult oral dosage is 8 mg (one tablet) or 10 ml Syrup (8 mg) should be administered 30 minutes before the start of emetogenic chemotherapy, with a subsequent dose 8 hours after the first dose. one 8mg tablet or 10ml syrup (8mg) should be administered twice a day (every 12 hours) for 1 to 2 days after completion of chemotherapy. Pediatric : For pediatric patients 4 to 11 years of age, the dosage is 4mg tablet or 5ml Syrup (4mg). The first dose should be administered 30 minutes before the start of emetogenic chemotherapy, with subsequent doses 4 and 8 hours after the first dose. one 4mg tablet or 5ml syrup (4mg) should be administered 3 times a day (every 8 hours) for 1 to 2 days after completion of chemotherapy.

2) Prevention of Nausea and Vomiting Associated With Radiotherapy:

Adults : For total body irradiation : One tablet (8mg) or 10ml (8mg) syrup should be administered 1 to 2 hours before each fraction of radiotherapy administered each day. For single high-dose fraction radiotherapy to the abdomen: One tablet (8mg) or 10ml (8mg) syrup should be administered 1 to 2 hours before radiotherapy, with subsequent doses every 8 hours after the first dose for 1 to 2 days after completion of radiotherapy. For daily fractionated radiotherapy to the abdomen : One tablet (8mg) or 10ml (8mg) syrup should be administered 1 to 2 hours before radiotherapy, with subsequent doses every 8 hours after the first dose for each day radiotherapy is given.

3) Postoperative nausea and vomiting :

Adults : The recommended dosage is 16mg given as two tablets (8mg) or 20ml syrup (16mg) 1 hour before induction of anesthesia. Or, as directed by the registered physician.

Packing : Ondason-8 : 3 x 10's tablets in blister pack.

Prescribing Description

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