Omeprazole USP
Composition : Omeprazole 20mg, 40mg Capsule
Indication : Healing of erosive reflux oesophagitis, Zollinger - Ellison syndrome, For the treatment of gastric ulcers, For the treatment of duodenal ulcers.
Dosage and administration : Erosive Reflux Oesophagitis : The recommended dosage is one 20mg Cosec capsule once daily before meal, given for 4 weeks. For those patients not fully healed after the initial course, healing usually occurs during a further 4 weeks treatment. Patients With Reflux Oesophagitis Refractory to Other Therapy : The recommended dosage is 40mg Cosec once daily before meal. Healing usually occurs within 8 weeks. Duodenal Ulcer : The usual dose is one 20mg Cosec capsule once daily, before meal for 4 weeks. In severe cases the dose may be increased to 40mg Cosec capsule once daily before meal. Gastric Ulcer : The usual dose is one 20mg Cosec capsule once daily before meal for 8 weeks. In severe cases, the dose may be increased to 40mg Cosec capsule once daily. Long-term maintenance treatment with Cosec capsule is not recommended. Zollinger-Ellison Syndrome : The recommended initial dosage is 60mg (40mg + 20mg) once daily before meal. The dosage should be adjusted individually and treatment continued as long as clinically indicated. More than 90% of patients with severe disease and inadequate response to other therapies have been effectively controlled on doses of 20mg - 120mg daily. With doses above 80mg daily, the dose should be divided and given twice daily. Elderly : Dose adjustment is not required in the elderly. Children : There is no experience of the use of Cosec capsule in children. Impaired Renal or Hepatic Function : Dose adjustment is not required in patients with impaired renal or hepatic function. Patients with severe liver disease should not require more than one 20mg Cosec daily or as directed by a registered physician.
Use in pregnancy and lactation : Omeprazole has been assigned to pregnancy category C by the FDA.
Packing :
Cosec 20mg Capsule : 5 x 10's capsules in blister pack.
Cosec 40mg Capsule : 6 x 7's capsules in blister pack.
